Uric Acid Metabolism Ppt

Kumar amarus: evidence for interaction with platelet activating factor receptor.CBD has enormous potential for the development as a drug candidate as depicted by diverse clinical and preclinical studies for the treatment of various neuropsychiatric disorders, arthritis, cancer and other diseases.Regardless of its therapeutic importance and interaction with the endocannabinoid system, denite pharmacological mechanism is not clearly established.Apart from medicinal research, there are a number of aspects which should be taken under consideration such as opinion of FDA, legal aspects of cannabis and international scenario during the drug development based on this plant.Despite its concrete denition in modern medicine, clinical and preclinical trials on cannabidiol have decorated encouraging results, and its application has been widened for the treatment of various neuropsychiatric disorders, arthritis and cancer.The leaets are lancelike with largest leaets underneath. cm long, slightly lensshaped with a blunt base.The surface colour of the leaets is dull light to dark green and usually unmarbled.The matured seeds are cultivated for bre and oil and for therapeutic uses. The oral intake of hot water extract of dried ower and leaf serves various purposes such as dyspepsia and gonorrhoea and as a nerve stimulant.The fresh leaves are taken for haemorrhoids, whereas its extract is used as insect repellent.The seeds are also useful for the treatment of hysteria, sleeplessness and diabetes and skin problems.Respiratory {|buy {Endurobol|Amiodarone ailments such as cough and bronchitis are cured by the mixture of dry leaf powder and honey.The seed oil is used to reduce cramps associated with lead poisoning related with constipation and vomiting.The leaf juice is used to treat wound and to treat swelling of wrenched joints.In the USA, uid extract is taken orally as a narcotic, antispasmodic, analgesic and aphrodisiac.The dried aerial parts are smoked by both sexes as an aphrodisiac.The absolute stereochemistry of CBD was determined in by converting it into methane carboxylic acid which was a stereochemically wellrecognized molecule. Even after several attempts has been made, a goodyielding route for the synthesis of cannabidiol is still unavailable in the literature. Among all side chain homologs, npentyl substituted one has been largely explored. All seven naturally available CBD analogues are having methyl conguration and cannabidivarinic acid have also been isolated.Furthermore, a monomethyl analogue of CBD has also been isolated from plant.Having similarity with other nonsteroidal antiinammatory drugs, selective inhibition of cyclooxygenase has been observed by CBDA. CBDNDC, available in low concentration in the plants owers, is likely to be a compound synthesized during photochemical transformation of CBD. A number of studies from literature have illustrated the pharmacological applications of CBD.In order to prove the CBD effect on symptoms of psychosis, studies were carried out on PD patients.For week, treatment shows improvement in the quality of life in PD patients. The anxiolytic and antipsychoticlike effects of cannabidiol are proven with animal studies. Further study on the patients suffering from schizophrenia when treated with CBD suggested CBD as safe and effective alternative prospect to be established as an antipsychotic drug.A report of CBD in animal models of PD also showed its neuroprotective effects suggesting its antioxidant properties which protect from degeneration of dopaminergic neurons.

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